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A hyperthyroid patient who was 30 years old had cholestatic jaundice as a result of methimazole.


Dr. Marwa Ibrahim Mohamed

Department of Medicine, Alexandria University, Alexandria, Egypt.

Correspondence to Author:  Dr. Marwa Ibrahim Mohamed


One of the most prevalent endocrine illnesses, particularly among females, is hyperthyroidism. In this case study, a 30-year-old female patient complained of pale stool, black urine, and yellowed sclera. She had previously experienced controlled thyrotoxicosis treated with methimazole a month prior. She began taking methimazole 20 mg a day, and after a month of medication, she had an acute cholestatic liver insult that had no other known cause. On withdrawal, symptoms and laboratory results lessened but did not return to normal. Beta blockers were first used to treat her disease, and then Prednisolone.

Hyperthyroidism; Methimazole; Cholestatic liver injury; Prednisolone


Dr. Marwa Ibrahim Mohamed. A hyperthyroid patient who was 30 years old had cholestatic jaundice as a result of methimazole... Japanese Journal of Gastroenterology, 2023.

Journal Info

  • Journal Name: Japanese Journal of Gastroenterology
  • Impact Factor: 2.709**
  • ISSN: 2832-4870
  • DOI: 10.52338/jjogastro
  • Short Name: JJOGASTRO
  • Acceptance rate: 55%
  • Volume: 4 (2024)
  • Submission to acceptance: 25 days
  • Acceptance to publication: 10 days


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