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A Meta-Analysis Evaluating The Effects Of Continued Versus Interrupted Aspirin Usage On The Risk Of Bleeding After Endoscopic Submucosal Dissection Of Stomach Neoplasms


Pellon G

Department of General Surgery, Karnataka, India

Correspondence to Author:  Pellon G


Background: reconciliation the chance of hemorrhage and thromboembolic events for patients United Nations agency use salicylate and wish to endure examination submucosal dissection (ESD) for viscus neoplasms may be a delicate method. the present pointers from completely different associations offer inconsistent recommendations. Methods: telephone system and EMBASE databases were searched through August 2017 for studies that compared the chance of post-ESD hemorrhage in patients United Nations agency continued salicylate vs. people who out of print salicylate preoperatively. Pooled odds ratios (OR) and ninety fifth confidence intervals (CI) were calculated employing a random-effect model, generic inverse variance methodology. The between-study heterogeneousness was quantified exploitation the letter datum and I2. Results: a complete of 5 studies that enclosed 700 patients were known. Our meta-analysis couldn’t demonstrate a considerably enlarged risk of post-ESD hemorrhage among the aspirin-continued cluster compared to the aspirin-interrupted cluster, the pooled OR being one.81 (95%CI zero.85-3.83). The applied mathematics heterogeneousness was insignificant, with AN I2 of twenty fifth. Conclusions: This meta-analysis couldn’t demonstrate that continuation of salicylate considerably will increase the chance of post-ESD hemorrhage. However, the analysis was restricted by the little sample size and also the experimental nature of the first studies. irregular controlled trials ar still required to clarify this risk.

Antiplatelet, aspirin, bleeding, endoscopic submucosal dissection, gastric neoplasms.


Pellon G. A meta-analysis evaluating the effects of continued versus interrupted aspirin usage on the risk of bleeding after endoscopic submucosal dissection of stomach neoplasms. Japanese Journal of Gastroenterology 2023.

Journal Info

  • Journal Name: Japanese Journal of Gastroenterology
  • Impact Factor: 2.709**
  • ISSN: 2832-4870
  • DOI: 10.52338/jjogastro
  • Short Name: JJOGASTRO
  • Acceptance rate: 55%
  • Volume: 4 (2024)
  • Submission to acceptance: 25 days
  • Acceptance to publication: 10 days


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