Authors:

Bali Aryan Rhayesteh, Johsen Kahraeian

Research Institute for Infectious Diseases of the Digestive System, Ahvaz Jundishapur University of Medical Sciences, Iran
Department of Internal Medicine, Ahvaz Jundishapur Uni versity of Medical Sciences, Iran

Abstract:

Background and objective: Diabetes is a risk factor for the development and progression of Non-Alcoholic Fatty Liver Disease (NAFLD), and measuring hepatic fibrosis is crucial to determine the prognosis in these individuals. Transient Elastography (TE) might be useful in the monitoring of fibrosis in NAFLD patients since it is a noninvasive, simple to use, and repeatable approach. Using the TE technique, this study aimed to examine liver stiffness in diabetic and non-diabetic individuals. Materials and Methods: After ruling out other reasons, 67 individuals (ranging in age from 20 to 60 years) with signs of fatty liver on sonography were separated into two groups: diabetics and non-diabetics. Then, following lab testing, patients were evaluated with TE, and their lab data and liver stiffness ratings were compared between two groups. Results: Both groups had similar demographic characteristics (including mean age, sex, BMI, AST, ALT, Total Cholesterol, LDL, and TG) (P>0.05). Diabetics had considerably higher mean liver stiffness ratings than non-diabetics (P=0.025). Only mean levels of AST and TG in F3 and F4 stiffness scores in diabetes individuals were substantially greater in comparison to lower stiffness scores (P0.05). Conclusion: Diabetes individuals are more likely to have significant liver fibrosis, and TE may be an effective monitoring tool in diabetic patients with liver fibrosis.

Keywords:
Nonalcoholic fatty liver disease, diabetes, fibroscan, transient elastography

Citation:

Bali Aryan Rhayesteh. Diabetic and non-diabetic patients with non-alcoholic fatty liver disease had their transient elastography results compared.. Japanese Journal of Gastroenterology 2023.