Correspondence to Author: Bibin CF, Parveen Malhotra, Rahul Siwach, Aditi, Avani Sharma, Abhishek Yadav, Gagandeep, Bharti Gupta. 

Department of Medical Gastroenterology, PGIMS, Rohtak, Haryana, India.

DOI: 10.52338/jjogastro.2026.5461

Abstract:

Introduction: Isolated hepatic tuberculosis is an uncommon and often under-recognized manifestation of extrapulmonary tuberculosis. Its presentation as a persistent sterile liver abscess poses significant diagnostic difficulty, particularly in the absence of microbiological confirmation.
Case report: We report a 42-year-old immunocompetent male with multiple hepatic abscesses unresponsive to prolonged broad-spectrum antimicrobial therapy and repeatedly sterile aspirate cultures. Despite appropriate conventional management, clinical and radiological findings remained static. In the context of endemicity and after systematic exclusion of common aetiologies, empirical antitubercular therapy was initiated following multidisciplinary evaluation. The patient demonstrated rapid defervescence within 72 hours, followed by sustained biochemical normalization and progressive radiological resolution.
Conclusion: This case highlights the limitations of conventional diagnostics in hepatic tuberculosis and emphasizes the role of informed, context-driven therapeutic decision-making in refractory hepatic abscess.

Keywords:Hepatic tuberculosis; Liver abscess; Sterile. Refractory hepatic abscess; Empirical antitubercular therapy..

Citation:

Dr. Parveen Malhotra, Isolated Tubercular Liver Abscess- A Rare Phenomenon. Japanese Journal of Gastroenterology 2026.