Authors:

Dr. Maira Omer

Department of Pharmacy administration and Clinical Pharmacy Xian Jiatong University, Xian China

Abstract:

Background Post-transplant junction biliary strictures stay refractory to scrutiny medical care in an exceedingly tidy variety of cases. The aim of this meta-analysis was to match fully-covered self-expandable metal and plastic stents within the management of post-transplant biliary strictures. Methods A meta-analysis was performed employing a random effects model; results were expressed as odds magnitude relation (OR) and mean standardized distinction. the first outcome was stricture resolution, whereas return rate when tube placement, treatment time, and safety of the procedure were the secondary outcomes. Results Through a scientific literature review till Oct 2017, we have a tendency to known seven studies, of that four were randomised controlled trials. Stricture resolution was slightly higher with metal stents, with no applied mathematics distinction between the 2 procedures (OR one.38, ninety fifth confidence interval [CI] zero.60-3.15; P=0.45) and low nonuniformity (I2=6%). Stricture return showed a non-significant trend in favor of plastic stents (OR one.82, 95%CI 0.52-6.31, P=0.35). scrutiny retrograde cholangiopancreatography with placement of metal stents offered a big improvement in terms of reduced treatment time (mean standardized difference: -3.58 months, 95%CI -6.23 to -0.93; P=0.008), however with a lot of frequent complications, though not considerably therefore (OR a pair of.34, 95%CI 0.75-7.25; P=0.14). Sensitivity analysis confirmed all the findings. Conclusion Metal stents seem to be a promising tool that may decrease treatment time, though there’s still no clear proof of their superiority over plastic stents in terms of effectivity.

Keywords:
Hepatocellular carcinoma, direct acting antivirals, hepatitis C, cirrhosis, interferon.

Citation:

Dr. Maira Omer. Metal versus plastic stents for anastomotic biliary stricture following liver transplantation Japanese Journal of Gastroenterology 2022.