Correspondence to Author: Vani Malhotra, Parveen Malhotra, Harman Singh, Sandeep Kumar, Senti, Anuj Sharma, Pranav Malhotra, Rahul Siwach. 

Department of Medical Gastroenterology and Obstetrics & Gynaecology, PGIMS, Rohtak and VMMC & Safdarjung Medical College, New Delhi

DOI: 10.52338/jjogastro.2025.5195

Abstract:

Introduction: Chronic hepatitis B virus (HBV) and C Virus (HCV) infection are important cause of cirrhosis of liver and Hepatocellular carcinoma (H.C.C). Majority of patients are asymptomatic and are detected incidentally before surgery, pregnancy, blood donation, dialysis and thalassemia treatment.
Aims and Objectives: To determine prevalence of HBV & HCV among blood donors and dialysis patients
Materials & Methods: It was prospective study conducted at Department of Medical Gastroenterology, Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, over a period of one year from 1st April, 2024 to 31st March, 2025 during which 40266 blood donors and 17474 dialysis patients were screened for HBV and HCV infections by HbsAg and anti HCV antibody test who were further confirmed by HBV DNA Quantitative and HCV RNA Quantitative test and treated as per scientific protocol.
Results:Out of the 40266 blood donors, 354 (0.88%) were HBV positive and 476 (1.18%) were HCV positive. On analysis of 17,474 dialysis patients, 130 (0.88%) were HBV positive and 476 (1.18%) were HCV positive
Conclusion: In view of asymptomatic nature in majority of HBV and HCV patients, manoeuvres to detect at early stage should be taken on broader front. The awareness regarding blood donation is one of them, as it is beneficial for both donor and recipient. The patients on dialysis are also at risk of getting these infections, hence are screened regularly for the same, so that extra care regarding strict infection control practices can be taken to reduce transmission to other patients.

Keywords: Hepatitis C virus, Hepatitis B virus, Blood Donation, Dialysis, HCV RNA Quantitative test; Anti HCV antibody, HbsAg, HBV DNA Quantitative

Citation:

Dr.Parveen Malhotra, Spectrum of HBV & HCV Among Blood Donors and Dialysis Patients at Tertiary Care Center of Northeren India.Japanese Journal of Gastroenterology 2025.